Supply issue with Xylocaine® 1% and 2% (lidocaine) with adrenaline 100micrograms/20ml (1:200,000) solution for injection vials


Please find a Medicine Supply Notification for: 

  • A Tier 2 medicine supply notification for Xylocaine® 1% and 2% (lidocaine) with adrenaline 100micrograms/20ml (1:200,000) solution for injection vials.  

DHSC and NHSE/I have now launched an online Medicines Supply Tool, which provides up to date information about medicine supply issues. The contents of this MSN can now be viewed on the Tool. To access the Tool you will be required to register with the SPS website

There have also been changes to the re supply dates of the medicines listed below. These communications were previously circulated via the NHSE&I commissioning routes. 

Please note, with reference to the MSNs detailed below for Desmopressin Octim Nasal Spray and DDAVP 100mcg/ml intranasal solution, resupply dates have been updated since last communicated on 27 October 2021. Please see below for the correct information:

Original MSN/SDA reference: MSN /2020/053
Date of original MSN/SDA: 02/10/2020
Supply issue: Desmopressin Octim Nasal Spray
Resupply date originally communicated: Mid 2021
Updated resupply date as of w/c 8/11/2021: Late 2023

Original MSN/SDA reference: MSN/2020/055-U
Date of original MSN/SDA: 15/10/2020
Supply issue: DDAVP 100mcg/ml intranasal solution
Resupply date originally communicated: Discontinued
Updated resupply date as of w/c 8/11/2021: Discontinued

Original MSN/SDA reference: MSN/2021/039
Date of original MSN/SDA: 27/07/2021
Supply issue: Clexane (enoxaparin) pre-filled syringes
Resupply date originally communicated: November 2021
Updated resupply date as of w/c 8/11/2021: October 2022

Please be aware this communication is also being circulated separately to all community pharmacies in England. 

Please note that for supply issues that have been categorised as tier 1 or 2, DHSC and the MSRG have requested that the NHSE&I commissioning routes are used to reach community pharmacy and GP practices. More serious supply issues are communicated via the Central Alerting System for action. 

If you have any queries please contact: DHSCmedicinesupplyteam@dhsc.gov.uk  

Please note, if the enquiry relates to any changes (additions or removals) to the mailing list and you are enquiring from a GP practice, please contact the NHSE&I Head of Primary Care commissioning.