Guidance on Rotavirus vaccination at 8 weeks of age in relation to the evaluation of the introduction of newborn screening for Severe Combined Immunodeficiency (SCID).


Following communication regarding the evaluation of screening for Severe Combined Immunodeficiency (SCID) from September 2021, and the impact on BCG vaccination, a further letter has been issued informing providers of action needed for administration of Rotavirus vaccine.

Rotavirus (Rotarix®) oral vaccine is a live vaccine given routinely from 8 weeks of age and is not recommended in babies with SCID. Practices are asked to update protocols to ensure that where SCID results (including SCID screening not offered) are received by the practice, they are available to the patient record for the practice nurse at the 8 week immunisation appointment.

As with the changes to the BCG programme, it is necessary to adopt this guidance for Rotavirus vaccination nationally to ensure consistency and safety for all babies nationwide.

Follow links for further information including information for HCPs and training slides, a flyer and leaflet for parents, and NHS vaccine pages.