Covid-19 Vaccine: MHRA precautionary advice on allergies issued

You may have seen media coverage, following two case reports of anaphylactoid reactions associated with administration of Pfizer BioNtech COVID-19 vaccine. In response, the MHRA has issued the following advice to healthcare professionals:

New MHRA advice:

  1. Any person with a history of a significant allergic reaction to a vaccine, medicine or food (such as previous history of anaphylactoid reaction or those who have been advised to carry an adrenaline autoinjector) should not receive the Pfizer BioNtech vaccine. 
  2. Resuscitation facilities should be available at all times for all vaccinations. Vaccination should only be carried out in facilities where resuscitation measures are available.

Professor Stephen Powis, National Medical Director for the NHS has also issued this statement:

“As is common with new vaccines the MHRA have advised on a precautionary basis that people with a significant history of allergic reactions do not receive this vaccination after two people with a history of significant allergic reactions responded adversely yesterday. Both are recovering well.”

Please share this for information with colleagues as appropriate.